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Sonic the Hedgehog #16 is the sixteenth issue of the Sonic the Hedgehog comic series by IDW Publishing.
||"Infection!" Sonic's been infected with a mysterious new virus and his speed seems to be his only saving grace. Can Sonic, Tails, and Tangle beat the disease before Sonic's beat? And who will be the virus' next victims?
- Previously: A brief recap of events that have happened in previous issues, reprinting relevant panels.
- Roll Call: A quick reference guide to new readers about the characters, providing data files on Sonic, Tails, Tangle, Dr. Eggman and Dr. Starline.
- Sonic Letters Squad: Reader letters and artwork, with replies from the comic staff.
- Free Digital Ashcan: Sonic the Hedgehog Annual 2019
- Sonic the Hedgehog #16 on IDW: US